Treatment: The therapy of overdosage with promethazine and codeine is essentially symptomatic and supportive. Only in circumstances of extreme overdosage or unique sensitivity do very important signs such as respiration, pulse, blood pressure, temperature, and EKG should be monitored. Activated charcoal orally or by lavage can be offered, or sodium or magnesium sulfate orally as being a cathartic. Interest really should be provided towards the reestablishment of ample respiratory exchange by way of provision of a patent airway and institution of assisted or controlled air flow.
Health care companies often prescribe promethazine to manage nausea, vomiting and relevant problems like movement sickness, dizziness and vertigo. It might also induce sleep, Management agony or reduce nervousness just before a health-related course of action.
The result of promethazine and/or codeine on later advancement and progress from the newborn is unknown.
Generally, dose choice for an elderly patient ought to be cautious, generally setting up in the small conclude of your dosing range, reflecting the greater frequency of lessened hepatic, renal or cardiac perform, and of concomitant disorder or other drug therapy.
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Postmarketing scenarios of respiratory depression, which includes fatalities, have been noted with usage of promethazine hydrochloride in pediatric patients considerably less than 2 years of age. A wide array of body weight-primarily based doses of promethazine hydrochloride have resulted in respiratory melancholy in these patients.
Anticholinergics - Concomitant usage of other agents with anticholinergic Attributes need to be undertaken with caution.
check with your medical doctor about the pitfalls and benefits of taking promethazine If you're sixty five years of age or older. Older adults must not generally take promethazine as it isn't as safe as other prescription drugs that could here be used to take care of the same ailments.
The procedure of option for ensuing hypotension is administration of intravenous fluids, accompanied by repositioning if indicated. In the event that vasopressors are considered for your management of significant hypotension which does not reply to intravenous fluids and repositioning, the administration of norepinephrine or phenylephrine need to be considered.
Scientific studies of promethazine formulations didn't include things like enough numbers of subjects aged 65 and over to ascertain whether they reply in another way from younger topics. Other described clinical working experience hasn't recognized differences in responses between the aged and youthful individuals.
Decreased Seizure Threshold - Promethazine could decreased seizure threshold. It ought to be used with caution in folks with seizure Issues or in people who will be utilizing concomitant medications, which include narcotics or community anesthetics, which can also affect seizure threshold.
To reduced your possibility, your physician really should have you take the smallest dose that works, and take it for that shortest doable time. See also The way to Use area To find out more about addiction.
She was also a member of the National Association of Legal Assistants. A mom and longtime affected individual, she has firsthand practical experience from the destructive effects prescription drugs can have on women as well as their children. A number of her skills incorporate:
Read through the Medication Guidebook if out there from a pharmacist Before you begin having this merchandise and each time you obtain a refill. In the event you have any issues, request your medical doctor or pharmacist.